System Cogniguard®

Cogniguard uses the vagus nerve, which is part of the parasympathetic nervous system, as a pathway for stimulating higher brain centres associated with processing memory traces. Numerous scientific studies have shown that with age (and in the course of certain diseases) the efficiency of the parasympathetic nervous system decreases in favour of the sympathetic nervous system, which brings many clinical consequences on the nervous, circulatory, and digestive systems. As a result of the decline in the parasympathetic nervous system, many diseases associated with ageing such as hypertension, heart failure, and most importantly, memory disorders occur.

How does our device work?

Based on our research, our engineering team designed the Cogniguard stimulator along with a mobile app for our patients and specialized software to collect cloud-based pacing data to support ongoing clinical trials. It’s a medical device for transcutaneous (non-invasive) stimulation of the auricular branch of vagus nerve. Stimulator consists of a headband with a built-in stimulator generating electrical impulses and a pair of electrodes placed under soft headphones. Device induces a small current reaching the surface of the skin at the entrance to the ear canal The Cogniguard device has passed the required safety and electromagnetic compatibility tests, the so-called EMC ( electromagnetic compatibility)

What the treatment process looks like?

Our priority was to create a device that is comfortable and easy to use. The treatment or electrostimulation process is very porous and takes place only during sleep, so it does not affect the patient's quality of life. The unique design and high quality of the headband materials allow for a comfortable and restful sleep while the device is in operation.

Clinical trials

Before starting clinical trials, we tested the safety and efficacy of stimulation on a group of over 20 healthy volunteers using functional magnetic resonance imaging (fMRI). In a series of studies, we demonstrated changes in limbic system activity in response to vagus nerve stimulation

Currently, our method is undergoing clinical trials among patients with memory disorders. The results obtained so far for Alzheimer patients and mild memory disorders show a significant improvement of memory parameters in more than 60% of cases with no significant side effects.

Do you want to join the project?

If someone in your family is ill or you would like to test our device yourself, write to us!

Together with us, change the world for the better.